Design Layer Visibility/Selectability
To toggle the visibility of a layer, right-click on the name of the layer in the Design Data pane and select Visibility > Show or Visibility > Hide.
To toggle the selectability of a layer, right-click on the name of the layer in the Design Data pane and select Selectability > Enabled or Selectability > Disabled.
You can also toggle the visibility/selectability of multiple layers (and nodes) using a button on the local toolbar in the Design Data pane:
This command is also accessible via the Quick Access Toolbar. See: Design Panel Commands
Toggle Explorer
In the Design Data pane, you can also toggle the visibility/selectability of all layers and nodes, or only show those layers and nodes that are loaded in the Design Window or the Animation View.